00:03 — Why perimenopause and menopause are critical stages in women’s health and why they deserve more attention.
02:18 — Breaking down the flawed 2002 Women’s Health Initiative study and its impact on hormone therapy misconceptions.
09:01 — How menopause impacts brain health and the role of HRT in reducing Alzheimer’s and dementia risk.
11:21 — The shocking bone density loss that occurs in the 5–7 years around perimenopause — and how to protect yourself.
13:44 — When perimenopause really starts and why most doctors get little to no menopause education.
16:03 — Environmental toxins as hormone disruptors — and how to reduce exposure.
18:27 — New research on nutrition interventions for menopause-related mood, metabolic, and cardiovascular health.
20:47 — The power of fiber, gut microbiome diversity, and short-chain fatty acids for hormone health.
30:06 — The holistic approach: combining HRT, nutrition, and lifestyle changes for optimal women’s health.
32:21 — Final message: Women don’t have to accept being dismissed — you can and should advocate for your health..

Resources & Links: 

Estrogen, Alzheimer’s & Osteoporosis: Perimenopause + Menopause Uncovered

Perimenopause, Menopause & Beyond: What Every Woman Needs to Know About Hormones, Nutrition & Functional Medicine

Menopause isn’t the end of vitality — but misinformation, stigma, and poor medical training have left too many women suffering needlessly. In this episode of The BeingBrigid Show, Brigid Titgemeier unpacks the powerful takeaways from an FDA roundtable on hormone replacement therapy, while weaving in her own decade-long experience helping women balance hormones through functional medicine and targeted nutrition.

You’ll hear the latest research on hormone therapy safety, how menopause affects brain health, bone density, and metabolic health, and why lifestyle changes — from nutrition to reducing toxic exposures — are essential in every stage of women’s health.

Whether you’re approaching perimenopause, in the thick of symptoms, or post-menopause and looking to reclaim your energy, this episode is your guide to understanding your body and making empowered decisions.

A Deeper Look at Hormones, Menopause & Functional Nutrition

For decades, women have been told that hormone replacement therapy (HRT) increases risks of breast cancer and heart disease. In reality, the data from the 2002 Women’s Health Initiative was misinterpreted and based on older populations. Recent FDA discussions show that for many women — especially when initiated earlier in perimenopause or near menopause — HRT can lower the risk of chronic diseases, improve bone density, protect brain health, and reduce long-term inflammation.

Breaking Down the Fear Around Hormone Therapy

Two-thirds of Alzheimer’s cases are in women, and evidence shows that the hormonal changes of menopause contribute to this vulnerability. Estrogen decline impairs how the brain uses glucose for fuel and accelerates beta amyloid buildup, directly impacting cognition and mood. At the same time, women lose 15–20% of bone density in just five to seven years around menopause, drastically increasing osteoporosis and fracture risk. With bone loss comes a higher risk of disability, frailty, and even mortality — yet few women are screened early enough.

Nutrition & Lifestyle as Hormone Regulators

Functional nutrition and lifestyle medicine are powerful tools for protecting women’s health through every stage — from perimenopause to post-menopause. An anti-inflammatory diet rich in vegetables, fiber, lean protein, and omega-3s supports hormone balance, insulin sensitivity, and gut health. Adequate protein intake is essential for muscle and bone strength, while fiber fuels the gut microbiome and produces short-chain fatty acids like butyrate that lower inflammation and help regulate estrogen.
Lifestyle changes like reducing environmental toxins, improving sleep, managing stress, and moving daily are equally essential. Environmental chemicals, fragrances, and plastics can act as endocrine disruptors, worsening hormone imbalances. Meanwhile, poor sleep and chronic stress fuel insulin resistance and increase risk of pre-diabetes, thyroid dysfunction, and cardiovascular disease.

A Holistic, Empowered Approach to Women’s Health

The Overlooked Impact of Menopause on Brain & Bone Health