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Michelle Sirmons

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What if the reason your weight won’t budge… isn’t calories — but blood sugar swings? GLP-1 medications are everywhere right now. But whether you’re taking one or not, this episode will help you understand what actually drives sustainable fat loss, stable energy, and long-term metabolic health — especially in perimenopause and post-menopause.

What You’ll Learn In This Episode:

  • Why GLP-1 medications don’t automatically stabilize blood sugar
  • The hidden risk of muscle loss and sarcopenia during weight loss
  • Why protein becomes essential during perimenopause and menopause
  • How resistant starch and fiber naturally support GLP-1 production
  • The connection between gut health, inflammation, and cravings
  • Why chewing your food and eating in a calm state improves hormone health
  • Lab markers every woman over 40 should track (A1C, fasting insulin, DEXA scans)
  • How food as medicine supports sustainable body composition changes

Timestamps:

  • 00:00 Introduction to Brigid and Michelle
  • 01:54 Working with clients on GLP-1s and blood sugar stabilization
  • 04:53 Risks of blood sugar fluctuations and nutrient deficiencies
  • 07:12 Key nutrition principles for women over 40 on GLP-1s
  • 08:30 Stabilizing blood sugar for better energy and health
  • 12:00 The role of protein in aging and muscle preservation
  • 15:58 Natural ways to support GLP-1 production through diet
  • 17:33 The importance of fiber and resistant starch for gut health
  • 20:15 Enhancing GLP-1 secretion with amino acids and omega-3s
  • 21:38 How to optimize digestion and reduce bloating
  • 22:44 Foundational habits for long-term health and vitality
  • 29:21 Tracking health markers and symptom improvements
  • 36:25 Empowering women at any age to thrive and flourish

GLP-1s, Blood Sugar & Muscle Loss in Women Over 40

GLP-1 medications are reshaping the weight loss conversation—but are they addressing root causes or simply lowering A1C on paper?

In this powerful conversation, I sit down with Michelle Sirmons, one of our registered dietitians at BeingBrigid Functional Nutrition, to break down what women over 40 truly need to focus on: blood sugar stability, muscle preservation, protein intake, gut health, and consistency. Because your body isn’t broken — it just needs the right inputs.

Blood Sugar Stability (Even on GLP-1s)

GLP-1s may lower A1C, but that doesn’t guarantee stable blood sugar throughout the day. Women can still experience:

  • Glucose spikes and crashes
  • Energy dips
  • Increased cravings
  • Elevated cortisol from skipped meals
  • Chronic inflammation

Appetite suppression often leads to undereating, which increases stress hormones and metabolic strain—especially in women over 40 who are already more vulnerable to insulin resistance and hormonal shifts.

Muscle Loss, Sarcopenia & Protein Needs

Up to 30% of rapid weight loss may come from lean muscle. This matters because muscle supports metabolic rate, bone density, and insulin sensitivity. As estrogen declines, muscle loss accelerates, increasing risk for sarcopenia, osteoporosis, insulin resistance, and chronic inflammation.

Adequate protein (around 30g per meal) and strength training become essential—not optional—for protecting long-term body composition and metabolic health.

Natural GLP-1 Support Through Gut Health

GLP-1 is also produced naturally in the gut. Short-chain fatty acids, created when resistant starch and fiber are fermented by gut bacteria, help improve insulin sensitivity, reduce liver glucose output, increase satiety and lower inflammation.

Most women consume only 12–15g of fiber daily. Targeting closer to 30g with diverse sources—beans, whole grains, vegetables, nuts, seeds, and resistant starch—supports gut health, hormone balance, and sustainable blood sugar regulation.

Key Labs for Women’s Metabolic Health

Beyond symptom improvements, objective markers matter. Key labs include:

  • A1C (goal ? 5.4)
  • Fasting insulin (~5)
  • Fasting glucose (70–85)
  • Lipid panel
  • Nutrient deficiencies
  • DEXA scans
  • Body composition tracking

Monitoring muscle mass—not just scale weight—is especially important for women using weight loss medications.

Food as Medicine & Root Cause Healing

Your body is not broken. Fatigue, cravings, inflammation, stubborn belly fat, and blood sugar imbalances are signals—not flaws.

Through consistency, nutrition accountability, and personalized functional nutrition, women regularly experience:

  • Improved energy
  • Reduced inflammation
  • Fewer cravings
  • Better sleep
  • Sustainable body composition changes
  • Even reversal of pre-diabetic markers

Not through restriction—but through anti-inflammatory, blood sugar–stabilizing meals that nourish the body at its root.

Resources & Links:
+ Watch the full episode on YouTube

+ Join the TENTH Round of The Blood Sugar Reset 

+ Explore The Being Collective Membership 

+ Brigid’s Website

+ Brigid’s Instagram

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GLP-1s for Women’s Health: Combating Muscle Loss & Blood Sugar Reset with Michelle Sirmons, RD

Brigid Titgemeier MS, RDN, LD, IFNCP
February 24, 2026
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